BIOM 3090 Study Guide - Final Guide: Heart Failure, Ventricular Hypertrophy, Cardiac Glycoside
Document Summary
Same drugs as hypertension + cardiac glycosides. Inability to meet needs for oxygen and nutrients of body, inadequate delivery to tissues. Ways to categorize: systolic hf: reduced contractility, diastolic hf: reduced filling, left hf: affects delivery to body, right hf: affects delivery to lungs. Causes: myocardial damage (80%), hypertension, infection, genetic/congenital abnormality, chemical toxicity. Sodium and water retention blood volume and pvr: fluid retention and vasoconstriction . Volume in veins pressure in returning blood stretching of cardiac muscle strength of contraction (frank- Starling curve: fibers need to be exactly spaced apart to maximize contraction: if you separate them a lot, they will contract harder! Heart may function normally at rest but may fail during exercise/stress. If co returns to normal, renal output also returns to normal. Severe damage (cid:272)a(cid:374)"t (cid:271)e (cid:272)o(cid:373)pe(cid:374)sated for by raas, sns, or ventricular hypertrophy. Excessive stretching further weakens heart (not maximally contracting) Excess fluid in venous system can leak into tissues edema (due to high pressure)