[MBG 2040] - Midterm Exam Guide - Everything you need to know! (23 pages long)

• School: University of Guelph
• Department: Molecular Biology and Genetics
• Course: MBG 2040
• Professor: Baozhong Meng

Document Summary

Chapter 10- replication of dna and chromosomes (220-249) Dna replication occurs semi conservatively, is initiated at unique origins and usually proceeds bi-directionally from each origin of replication. In humans, dna replication occurs at the rate of about 3000 nucleotides per minute. In bacteria, about 30 000 nucleotides are added to a dna chain per minute. Synthesis of dna involves three steps: chain initiation, chain extension/ elongation, chain termination. E. g. adenine in the parent strand will serve as template via hydrogen bonding potential for the incorporation of thymine in the complementary strand: this mechanisms of replication is called semi-conservative replication because the parental molecule is half conserved. In conservative replication the parent double helix would be conserved and a new progeny double helix would be formed. In dispersive replication, segments of both strands of the parent dna molecule would be conserved and used as templates for the synthesis of complementary segments which would be joined producing progeny dna strands.