MBG 2040 Midterm: MBG 2040 Midterm Notes - Panel 1

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Genes comes in multiple forms called alleles. Genetic information is transferred from dna to rna to protein. One of two or more alternative forms of a gene. An individual organism possessing two different alleles at a locus. An individual organism possessing two of the same alleles at a locus. Gregor johann mendel discovered basic principles of heredity. Monohybrid cross study of a single trait. Dihybrid cross study of two traits. Alleles are completely independent carrier of genetic information. Dominant allele completely eclipse the trait of the recessive allele. Different alleles assort independently, they are not connected. Pedigree analyses used to calculate the probability of a phenotype of individuals within a family tree. Null (amorphic) alleles = total loss of function (a non-functional or no gene product is produced) Hypomorphic alleles = partial loss of function (a poorly functioning gene product is produced) Dominant hypermorphic alleles = negative phenotypic consequences due to the over- production or increased activity.

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