NUTR 3210 Study Guide - Final Guide: Microcytic Anemia, Menkes Disease, Hemosiderosis
5 Apr 2017
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Copper varying content in food, affected by the preparation, rich in oyster and shellfish. Heme in animals, non-heme in plants mostly bound to aa women higher than men, higher during pregnancy microcytic anemia. Rich in oysters, present in meat, nuts, dairy etc complexed with nucleic acid and aa. Accounts got git losses, enzymes, unabsorbed zn in elderly, veg, children, inadequate cell division, retardation in children, poor wound healing, delayed sexual maturation, impaired taste lead to cu deficiency, neurological problems, numbness, metallic taste, nausea in si. Mediated by zip4, and diffusion released from aa by hcl and pepsin, absorbed a little in stomach, majority in si. Copper transporter 1 and divalent metal trnasporter 1, reduced to cu1+, Absorption site ferric reduced to ferrous in stomach and si, absorbed in si. Inhibitor non-heme by divalent metal transporter 1, heme by heme carrier protein 1, then hydrolyzed by heme oxygenase bound to transferrin in blood.
