[PATH 3610] - Final Exam Guide - Everything you need to know! (36 pages long)

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Cecil Foster

Document Summary

Degeneration is when part of the cell begins to break down; eventually, this will cause cell death if it proceeds to a point where cell recovery is no longer possible (irreversible degradation: ulcer, pus, burn. Cells in the body die all the time as part of a normal, natural process; but abnormal death, is part of a diseased state. Injury: the result that occurs when the demand (insult) is exceeds the ability of the cell to adapt. 3 responses to stimulus/injury: adaptation - reversible - (stimulus, degenerate - reversible - (injury, death - irreversible - (injury) Hypertrophy (increase in size of cells: all cells, atrophy is the opposite (when a tissue or cell reduces its size; either by reduction of number of cells or reduction of cell size) Hyperplasia (increase in production rate of cells: cells respond with hyperplasia in certain locations, labile and stable cells. Permanent (post-mitotic) cells: neurons, cardiac myocytes, skeletal myocyte (hypertrophy)