PATH 3610 Study Guide - Final Guide: Pulmonary Edema, Haemophilus Influenzae, Mucociliary Clearance

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Rob Foster

Document Summary

Principles of respiratory disease: respiratory anatomy and function, edema, lung defences, bacteria pneumonia and tuberculosis, alveolar injury: interstitial pneumonia and the acute respiratory distress syndrome, airway disease: infectious, asthma, copd, lung cancer. 300, 000, 000 alveoli; cover 80m2 = 1 tennis court. Alveoli are fine and branching delicate functional structures; vulnerable. Illustrates the vulnerability of the lung; doesn"t take a lot for something to have a functional effect. Capillary transit time: 0. 75sec (0. 25 seconds required for o2 exchange) Ventilation (need proper functioning of brain, muscles, airways, compliance) Defense: against airborne micro-organisms (lungs have to be kept sterile) How to measure lung function : arterial blood gas analysis. Low pao2 = hypoxemia (lower amounts of oxygen in the blood) High pao2 = hypercapnia (increased amounts of co2) Airflow and volume measured using a spirometer can be measure quite easily in humans, helped determine severity. Forced vital capacity: total volume of exhaled air.