PATH 3610 Study Guide - Final Guide: Oxidative Phosphorylation, Intracellular Ph, Enzyme Inhibitor

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Define and describe the following: describe lethal and nonlethal cell injury, and apoptosis. A: nonlethal cell injury: an abnormality of cell biochemical function and/ or a recognizable structural change. Is potentially reversible or may result in cell death (necrosis). This may result in a compensated state in which cells may degenerate for a time then reach a static condition where the inefficient function is sufficient to maintain the life of the body. Lethal cell injury: irreversible necrosis (local cell death). The most important targets of injurious stimuli are the mitochondria (site of atp production), cell membranes (integral to cell membrane homeostasis), protein synthesis, the cytoskeleton, and the cell genetic apparatus. A form of cellular suicide that mostly occurs as a component of the normal development and physiology of the body: outline the causes of and describe the outcomes of impaired cellular energy production.