PATH 3610 Study Guide - Final Guide: Acute-Phase Protein, Granulation Tissue, Natural Killer Cell

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Rob Foster

Document Summary

Labile cells constant turnover is seen (epithelial cells and bone marrow) Permanent cell- post mitotic cell, can not be replaced (myocardial, neurons, skeletal muscle) Stable cell- not normally dividing but can be replaced by a stem cell (fibroblast, smooth muscle) Cytokine- chemical message sent from one cell to another. Embryonic stem cell- pluripotent, can turn into any cell type. Necrotic- gross macroscopic appearance of dead tissue, can be coagulative, liquiditive of caseous. Apoptosis- programmed cell death cells appear to shrink. Intrinsic cellular aging- due to chromosomal shortening and clock genes. Extrinsic cellular aging- due to wear and tear, odfr. Healing- repair via regeneration and scar tissue formation. Innate immunity- defences prior to exposure, no memory and non selective. Acquired immunity- mediated by b and t cells following exposure to an antigen and exhibits specificity. Inflammation- a series of physiological events triggered by invading microbe and/ or tissue damage.