BIOL331 Final: BIOL 331 Exam Review
5 Aug 2016
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Biology 331: advanced cellular biology final exam review. Network of filamentous proteins responsible for cell strength, shape, and movement. Three main types of filaments: actin filaments: cell surface shape, movement, microtubules (mts): intracellular transport, positioning of organelles, mitotic spindle (cytokinesis, intermediate filaments (ifs): mechanical strength. Cytoskeletal proteins associate with hundreds of accessory proteins which regulate filament connections (w/each other and other cell components); control assembly and disassembly of filaments; motor proteins that hydrolyze. The cytoskeleton can be rapidly re-organized for cytokinesis and cell movement: e. g. during cytokinesis: actin network form lamellipodia + filopodia to move and mts emanate from mtoc. Mts form mitotic spindle first, then actin forms contractile ring during cytokinesis. Protofilaments are long, linear strings of filament subunits joined end- to-end associated laterally to form actual filament, twisting around each other to form a helical structure held together by weak non- covalent interactions.
