BIOL341 Midterm: 341 mid term 1
8 Mar 2017
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Document Summary
Pathogens cause disease pathogenesis: organisms must breach hosts natural barriers mucus, hair, saliva, tears. Functions to maintain homeostasis and provide defense against foreign entities. Pathways interact with each other to protect us and are integrated with a number of body systems: antigens: little bits of pathogens recognized by recptors on immune cells. Creates tailored immune response depending on the type of organism, where the infection is, the location of the microbe in relation to the cell. Same response each time: uses barriers, phagocytes, prrs so no pathogen goes undetected, humoral mediators: proteins in the blood. Cellular mediators: macrophages, granulocytes, nk cells, prrs (germ-line encoded (the same every time)) Cellular mediators: t cells, infected self-cells specific antigens. Cells with viable receptors are clonally selected: deletion of self-recognizing lymphocytes. Work together: activation of innate produces cytokines which stimulate and direct adaptive responses, adaptive helps innate or uses components of it to eliminate pathogens.
