BIOL 200 Study Guide - Final Guide: London Dispersion Force, Signal Peptidase, Golgi Apparatus
Document Summary
Topic 4. 1 - introduction & protein import: explain the structural and functional relationships between the different compartments of the endomembrane system, and identify them on micrographs. Proteins must enter from start of each pathway. Once proteins enter er, they never return to cytosol naked are carried by vesicle transport to other parts of system. Er = flattened membrane cisternae & tubules. Ensures properly folded proteins move on, and misfolded ones are dealt with so that the components can be recycled. Rer = cytosolic side has attached ribosomes that are synthesizing proteins for import. Site of synthesis for proteins destined for secretion, lysosomes, or into er. Ser = site of lipid and steroid synthesis. Proteins destined for here must enter at er. (3) mechanisms to protein targeting and import into the nucleus : describe how proteins are targeted and imported into the er and compare these.
