MICB 202 Study Guide - Final Guide: Opportunistic Infection, Virulence Factor, Intracellular Parasite

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15 Aug 2017
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Topic 4: pathogenicity & virulence mechanisms of pathogenic bacteria. E(cid:454)plai(cid:374) koch"s postulates, their sig(cid:374)ifica(cid:374)ce a(cid:374)d state 2 situatio(cid:374)s (cid:449)here the(cid:455) (cid:373)a(cid:455) or (cid:373)a(cid:455) (cid:374)ot appl(cid:455) Explain origin of pathogenicity as well as difference btw pathogenicity & virulence. Pathogenicity: potential ability of bacterium to cause disease (qualitative- either pathogen or not) Virulence: measure of relative ability of pathogen to cause disease (depends on host pathogen interaction - quantitative) Explain difference btw pathogenic & opportunistic pathogen. Pathogen: (cid:271)a(cid:272)teriu(cid:373) (cid:272)apa(cid:271)le of har(cid:373)i(cid:374)g (cid:374)or(cid:373)al host (cid:894)does(cid:374)"t (cid:373)ea(cid:374) it (cid:449)ill(cid:895) Opportunistic pathogen: bacterium that is only capable of harming a compromised host. Describe potential outcomes of an encounter with a pathogen in terms of infection & disease and steps required to establish successful infection & cause disease. Potential outcomes from encounters w/ bacteria from the environment. Colo(cid:374)ize (cid:271)od(cid:455) & (cid:271)e(cid:272)o(cid:373)e part of (cid:271)od(cid:455)"s (cid:373)i(cid:272)ro(cid:271)iota. Colonize body & establish infection in body. Establish an infection in body & cause disease.

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