BIO152H5 Lecture 18: UTM BIO152 lecture 18 - Biology

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Published on 16 Aug 2020
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November 15, 2018
Biology Lecture 18 Chapter 24
Phenylketonuria (PKU) is extremely common in Ireland, affecting approximately 1 in 4500 live births. Assuming
that the population is in Hardy-Weinberg equilibrium, what is the frequency of PKU carriers?
a) 0.022%
b) 98.5%
c) 2.9%
d) 1.49%
e) 2.2%
The incidence of phenylketonuria (PKU), an autosomal recessive genetic disorder, is approximately 1 in 4,500
in Ireland. Assuming Hardy-Weinberg
equilibrium, what is the probability that a
phenotypically normal Irish female, with
no family history, and a phenotypically
normal Irish male, with an affected sister,
will have a child with PKU?
a) 0.028%
b) 0.49%
c) 0.55%
d) 1.96%
e) 2.2%
In a group of 500 people, the frequency of genotype NN is 40%. Assuming both autosomal inheritance and
that the population is in Hardy-Weinberg equilibrium, how many individuals would you expect to have the MN
genotype?
a) 68
b) 232
c) 300
d) 200
e) 258
Concept 23.4
- A hybrid zone is a region in which members of different species mate and produce hybrids
- Hybrids result from mating between species with incomplete reproductive barriers
- Hybrids often have reduced fitness compared with parent species
- When closely related species meet in a hybrid zone, there are three possible outcomes:
Reinforcement
Fusion
Stability
Reinforcement: Strengthening Reproductive Barriers
- When hybrids are less fit than parent species,
reinforcement of reproductive barriers may
occur through strong selection for prezygotic
barriers
- Over time, the rate of hybridization decreases
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