BIO315H5 Midterm: Test 2 Review - Lecture 9

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Knowing how to get proteins synthesized in the cytosol to their correct location. Sub-cellular components have specific spatial relationship to one another. Colors represent 2 major topolocical spaces that a region of the cell belongs to. Membrane enclosed organelles have same topological state as extracellular space. If organelles are in the same colour, means they belong to same topological state. Contents from one organelle can be transferred to another organelle. Topologically equivalent compartments in the secretory and endocytic pathways in a eukaryotic cell. Compartments are topologically equivalent if they can communicate with one another (in sense that molecules can get from one to the other without having to cross a membrane) Blue arrows indicate extensive outbound & inbound vesicular traffic. Some organelles (mitochondria) do not take part in this communication process and are isolated from the vesicular traffic between organelles. Ribosomes are found in cytosol either as free ribosomes or attached to er.