BIO375H5 Study Guide - Final Guide: Inflammatory Arthritis, Infliximab, Trastuzumab

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12 May 2020
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Chemotherapy: severe side effect profile real patients willing to take chance of benefit, phase 2 pilot study despite toxicity, determine whether or not we want to commit resources to the project, small group of patients tested. Secondary endpoints are the rest of the potential benefits: an endpoint can be a primary endpoint and a surrogate endpoint, true endpoint vs. Surrogate endpoint: surrogate endpoint correlated to what you"re interested in, ex. Aids patients endpoint was mortality: concentration of virus in blood plasma longevity connected to that became the endpoint, allows shorter trials and lowers cost, ex. What are their goals: quarterly earnings statements, every 3 months firms issue earnings reports(publicly traded) Investor community (or shareholders) will sell / buy shares, impacting share price in response: small biotechs usually have no earnings & instead report on product testing progress & patient recruitment for clinical trials. Lemonade stand has a good return but oil platform may have to provide 50% rate of return.