BIOC19H3- Final Exam Guide - Comprehensive Notes for the exam ( 76 pages long!)
30 Nov 2017
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What is developmental biology: the study of the developing animal from the fertilized egg right through to the adult stage, study of the development of specific tissues (e. g. formation of blood cells) Can be studied at 2 levels: morphological level, molecular level. Regulation of gene expression underlies morphological changes seen in development. E. g. gene hmga2 key gene regulating height in people mechanism unknown but thought to increase cell production. But many genes often work together to achieve a morphological trait including height. Historical advances in developmental biology: phase 1: descriptive studies, phase 2: comparative studies, phase 3: experimental embryological developmental studies, phase 4: molecular biology studies, phase 5: transgenic plants and animals. Phase 1: descriptive studies: visual observations, microscopic observations. Ancient times (naked eye) ~16th century (single lens magnifiers) 18th century-present (compound microscopes) Advances in glassmaking permitted magnifying lenses to be developed later incorporated into: Early microscopes to make descriptive observations with inc. magnification.
