MICR 200B Study Guide - Midterm Guide: Nitrogenase, Lactose Permease, Operon

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15 Jan 2018
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Topic 3c: genetics and molecular biology gene regulation: Bacterial environments may be unstable, so they need to be able to adapt to rapid changes (through changing gene expression and the production of different proteins) Many levels of regulation: including the rates of transcription, mrna stability, rates of translation, post-translational regulation. Housekeeping genes: genes that are expressed all the time and are required for growth, replication, ect. Constitutive genes: genes that are continuously turned on. Inducible genes: genes that can be turned on under speci c conditions (with the presence of a signal) Repressible genes: genes that can be turned off under speci c conditions (with the presence of a signal) Negative inducible: the binding of a repressor to an operator sequence inhibits transcription, the signal causes a dissociation of regulatory protein from dna. Negative repressible: the binding of a repressor to an operator causes binding of regulatory protein to dna.

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