Biochemistry 2280A Study Guide - Quiz Guide: Thymidine Triphosphate, Polynucleotide, Deoxycytidine Triphosphate
4 Jun 2020
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Consists of chain of monomers -> nucleotides. Phosphate group (alpha (1st) beta (2nd) & gamma (3rd) phosphates) Types of bases in dna: adenine & guanine -> purines, cytosine & thymine -> pyrimidines. Bases attached to deoxyribose sugar by |b-n-glycosidic bond. Thymine: 2"-deoxythymidine 5"triophosphate -> dttp t: adjacent nucleotides are joined by phosphodiester bonds -> between phosphate group of one nucleotide & hydroxyl group of another -> strand of dna. 5th carbon of each deoxyribose ring bonded to 3rd carbon of next ring. 3 oh terminus: end of a polynucleotide chain, terminating with a hydroxyl group attached to the 3 -carbon of the sugar. 5 p terminus: end of a polynucleotide chain, terminating with a mono-, di- or triphosphate attached to the 5 -carbon of the sugar: dna -> double-stranded. Different types of dna: b-dna most common -> predominant, a-dna rare -> forms in dehydrating conditions, z-dna (naturally) found with b-dna in certain regions.
