Biochemistry 3381A Study Guide - Quiz Guide: Semiconservative Replication, Dna Replication, Polynucleotide
27 May 2020
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Dna, rna & protein synthesis: describe evidence that dna carries genetic information. Mendel: coined units of inheritance (later turned genes) Morgan: studied drosophilia genes are on chromosomes . Griffith: experiments on strains of a pneumoniae bacterium passed genetic material from one bacteria to another there is an inheritance factor. Avery: destroyed everything but the dna and transformation still occurred. Hershey-chase: worked with virus t2: discovered that only the dna enters the cell. Chargaff: composition of dna differed between species: show that dna is an anti-parallel double-stranded polynucleotide in which base pairing plays a crucial role. Phosphate (polar, hydrophilic) outside: explain the meselson-stahl experiment to demonstrate semi-conservative replication of dna. Semi-conservative model: each strand of dna serves as a template to make a new, complementary strand. Conservative replication: dna replication results in one molecule that consists of both original dna strands) and another molecule that consists of two new strands.
