Physiology 2130 Study Guide - Midterm Guide: Anterior Pituitary, Follicular Cell, Thyroid

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Various responses depending on what tissue is signalled. Target cells have receptors that they bind to chemical signal secreted into bloodstream to act on a distant tissue. Can be produced in glands or within cells of an organ oxytocin, adh/vasopressin. O: uterine contractions during labour, release of milk. Relationship between location of receptor for hormone and the action it performs. Receptor in plasma membrane: tends to alter existing proteins (ex. through g protein cascade) Receptor inside cell: tends to affect production of new proteins (gene transcription), takes longer. Releases lots of diff hormones in response to hypothalamus. Anterior vs. posterior pituitary gland infandibulum stalk that connects the hypothalamus to the pituitary gland. Consequences of mutation: diabetes insipidus - urinate more. Connection between the two capillary beds (one in infundibulum, the other in the anterior pituitary) Hypothalamus releases hormones -> anterior pituitary releases hormones. Crh -> acth -> corticotroph cells, adrenal glands. Dopamine inhibits prolactin -> mammary glands, milk production.