PS268 Study Guide - Final Guide: Salvia Divinorum, Albert Hofmann, Salvinorin A

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20 Apr 2020
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Peyote (mescaline: hallucinogenic mushroom (lophophora williamsii, mescaline is the hallucinogenic chemical of peyote. Top part of mushroom is sliced and dried into thin disks, know as mescal buttons . Salvia: salvia divinorum, used for at least a 1000 years in shamanic rituals by mazatecs of mexico. 1992: gordon wasson and dr. albert hofmann bring to n. america first samples. It was a new hallucinogen that didn"t use lysergic acid: but without rituals and cultural background salvia did not have much effect on americans. 2002: dr. daniel siebert purifies salvinorin a, fortifies leaves up tp 100x the natural strength. Figures out that it binds to the kappa opiate receptors and not serotonin like most hallucinogens: now that it is purified and smoked it take soff in n. america, smoking it is 10000x stronger than chewing. Effects of smoked salvia: effects begin quickly: <20 seconds.

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