PSYC 362 Study Guide - Midterm Guide: Phenotype, Cell Adhesion Molecule, Cell Adhesion
19 Aug 2016
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Cell biology and society: healthcare, drugs, personalized medicine b. i. Sequencing the genome: bioterrorism, religious issues, government f. Immortality: bioterrorism, foxglove extract is called digitalis, used to treat heart disease, botulinum toxin, rnai, clinical trials macula degeneration, neurotoxins e. i. Anthrax: stem cells and regenerative medicine, def: totipotent, def: pluripotent, health applications c. i. Two companies: genzyme, bioheart: government, august 2001, private research, other cool developments, computer made out of neurons, reverse bioengineering c. Methods microscopy: history/background information, paradox a. 1. How does one prepare the specimen: abbe"s equation, problems with cells, light microscopes, bright- field/compound light microscope a. 1. No dyes are used: nomarski or differential interference contrast c. 1. Image is bright d. 1: polarizing light microscope e. 1. Used to visualize structures that are ordered, e. g. muscle cells f. 1970s concept of confocal was born f. 2. Manipulate the laser, illuminate a specimen spot by spot f. 4. Immunocytochemistry: vital fluorescence microscopy, mitochondrial dyes, cell membrane integrity dyes. Intracellular calcium: frap fluorescence recovery after photobleaching.
