[CAS BI 525] - Midterm Exam Guide - Ultimate 58 pages long Study Guide!

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Ne/bi525: lecture 1 (part 3: parkinson"s disease and diagnosis a. L-dopa dopamine: when symptoms occur 60-80% of dopaminergic neurons have died, pet c. i. Administer radioactive l-dopa: which can help identify healthy dopamine neurons c. ii. In pd, decreased signal (less healthy dopamine neurons) http://www. parkinson. org c. iii. L-dopa treatment intervention: leads to increased dopamine, rescue dopaminergic signaling (how does this happen) c. iv. 18f fluorodopa how advanced the pathology is. 18f fluorodeoxyglucose uptake during pd is decreased than in normal brain. Fdg any neuron: huntington"s disease and diagnosis, mri analysis a. i. Ne/bi525: lecture 1 (part 1: western blot: analytical technique used in molecular biology to detect specific proteins in a sample of tissue homogenate or extract b. Immunohistochemistry: proteins or 2nd products in tissue: common features and molecular pathways in neurodegenerative diseases, characteristics a. i. Can we look at this from a patient? a. i. 2. a. Goal of treatment: slow the diseases down because there is no cure a. ii. 2.

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