SAR HS 300 Study Guide - Midterm Guide: Prospective Cohort Study, Nonprobability Sampling, Random Number Table

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9/28 study design overview and observational studies (ecological, cross-sectional) Initial classification of subjects (disease or exposure status) Directionality of exposure measurement (risk factor disease or disease risk factor) Investigator manipulates both the study factor and randomly assigns subjects to the exposed control over the research setting and non-exposed groups. Neither manipulation of study factor nor randomization of study subjects. Makes careful measurement of patterns of exposures and disease in populations to draw. Descriptive: estimate disease frequency and trends inferences about etiology. Analytical: to generate and test hypotheses and suggest causation. Association between exposure & disease (measures of association) Start with n (number in sample) determine each subject"s exposure and disease status (a,b,c,d). Start with marginal related to disease status (a+c disease) & no disease). and (b+d. Determine disease development to complete interior cells. Prospective studies: start in the present and study groups into the future. Retrospective studies: look into the past for associations between suspected causative factors.

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