BIOL 3350- Final Exam Guide - Comprehensive Notes for the exam ( 33 pages long!)
Document Summary
The history in our genes - lecture 1 - 10/26/17. Think of it like the flip side of evolution, how things evolve. It"s a way of looking at the history of genes by looking back through time. The process by which, looking back through time, the genealogy of any pair of homologous alleles merges in a common ancestor. Gene tree - phylogeny when it refers to genes and alleles. Where they all come together is coalescence. (slide 2. ) graph a, tracing where individuals sent their alleles and who they sent them to. See where the red and black individuals connect back in time to see where they started from. (slide 3) across all those different genes, the coalescence for them happen at different times. Each loci or allele has its own coalescence. The branching patterns don"t always necessarily agree with coalescence. Nonsynonymous substitution - it changes the amino acid. This can cause problems, may change the function of the protein.