BIO 303 Study Guide - Midterm Guide: Alkaptonuria, Cystic Fibrosis, Hypophosphatemia
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Document Summary
The average length of looped dna = 300nm. Two genes on the same chromosome do not sort independently. Dna is replicated by using each strand as a template for synthesis of the complementary strand. All added at 3" end of the growing strand. Meiosis distributes replicated chromosomes to haploid daughter cells in two nuclear and cell divisions. Replication fork contains a complex of enzymes, including dna polymerase. Gyrase to relax supercoils formed by unwinding. Leading strand is used for continuous dna synthesis. Lagging strand is used in discontinuous synthesis. Without telomerase, lagging strands continuously shorten with remover of primer. In meiosis, recombinant products with new combos of parental alleles are generated by. Independent assortment of alleles on nonhomologous chromosomes. Crossing-over in premeiotic s between non sister homologs. Dihybrid meiosis = 50% recombinants indicates either that genes are on different chromosomes or that they are far apart on the same chromosome. Recombination frequencies can be used to map gene loci.
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