[BSC 4930] - Midterm Exam Guide - Everything you need to know! (44 pages long)

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7 Feb 2017
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Be familiar with the concepts of preformation and epigenesis as early theories relating to development. Fate mapping know what it is (labeling of cells/portions of the embryo with dye or other labels and following the label during development). Know the lof and gof mutations listed in the lecture slides. Understand the concepts of forward and reverse genetics, and be able to identify the strengths and weaknesses of each. Maternal effect mutations are mutations carried by the mother that effect her ability to deposit developmental factors in the egg, resulting in aberrant development of the zygote. Thus, for maternal effect mutations, the genotype of the mother determines if a phenotype is seen in the offspring. Confocal microscopy is a form of fluorescence microscopy that allows the user to image a specific focal plane. Be familiar with the 4 molecular methods we discussed to look at expression of mrna or protein.

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