NURS 2061 Quiz: Pharm Drug Cards (exam III)
Document Summary
Depresses the cns by inhibiting the conduction of impulses in the ascending reticular activating system, thus depressing the cerebral cortex and cerebellar function. Oral as a sedative and antiepileptic agent in treatment of generalized tonic-clonic and partial seizures. Liver failure, nephritis, porphyria, respiratory depression, pregnancy, addiction to barbiturates. Caution w/ acute or chronic pain, lactation, fever, hyperthyroidism, dm, decreased renal liver function, pulmonary and cardiac disease. Alcohol, chloramphenicol, diazepam, monoamine oxidase inhibitors, gabapentin, valproic acid, mephobarbital, primidone. Cns depression, possibly cognitive impairment w/ sedation, somnolence, Suicidal ideation, agitation, confusion, vertigo, nightmares, sjs (hypersensitivity reaction), sudden withdrawal = risk for status epilepticus statements of depression and suicide. Opioid analgesics enhance cns depression, phenobarbital, corticosteroids, doxycycline, estrogens, hormonal contraceptives, oral anticoagulants, tricyclic antidepressants = decreased effects. Incompatible w/ acidic solutions, amp b, chlorpromazine, diphenhydramine, insulin, vancomycin. Inadvertent intra-arterial injections can cause spasm of artery and gangrene.