BIOL 4124 : BIOL 4124 Final Study Guide
Document Summary
Bacterial dysentery: what organism causes amoebic dysentery, entamoeba histolytica - amoebic dysentery, what organism causes bacterial dysentery, shigella spp. Enteropathogenic escherichia coli (epec: where is epec found, developing countries, what is the pathogenesis of e. coli, destroy gut microvilli, no toxins, use bundle forming pili and intimin (adhesion) to attach to and disrupt epithelial cell. 5% of infections and the principal cause of acute renal failure in children under 5. Enteroinvasive escherichia coli (eiec: what are the symptoms of enteroinvasive e. coli (eiec), watery diarrhea that progresses to dysentery. Fever, abdominal cramps, malaise, vomiting: what is the pathogenesis of eiec, attach to mucosa of colon; invade by endocytosis using plasmid associated genes. Invade mucosa, divide, spread and destroy epithelium causing inflammation, necrosis and ulceration. Invades m cells, mucosal epithelial cells, stimulates production of fluids. Invade tissue and infect macrophages which carry them to spleen, liver & bone marrow.
