PSIO 532 Study Guide - Final Guide: Chronic Kidney Disease, Nephritis, Inulin
Document Summary
Clearance: the clearance of a substance is the volume of plasma from which that substance is completely removed per unit of time. Tm: the tm is the maximal transport rate of a substance by the renal tubules (secretion or reabsorption). 58 yo woman with long standing but stable chronic kidney disease due to lupus nephritis. She now develops multiple cysts in her kidneys, but the one on the left appears malignant (arrow). She wants to know what will happen if they take out the kidney with the tumor . will she need dialysis, etc. Think about this question as you go through the next few slidesthen we will use what we have learned to help answer her questions. The implications for clinical practice and the use of clearance concepts become very important and useful. -> only 90% of this total renal blood flow perfuses through the nephrons.
