PSIO 532 Study Guide - Final Guide: Nephron, Inulin, Tubular Fluid

• School: UNE
• Department: PSIO
• Course: PSIO 532
• Professor: Mueller

Document Summary

For glucose sglucose = 0 (glucose is not secreted) Initially the clearance is zero, but as ax (glucose) gets bigger and approaches infinity, The clearance would begin to approach the clearance line of inulin as the a(glucose) increases in the plasma --> this is why the excretion slope approaches that of inulin. At low aglucose, all the glucose that is filtered is reabsorbed from the tubular fluid, hence, (cid:374)o glucose appears i(cid:374) the uri(cid:374)e a(cid:374)d no glucose is (cid:862)cleared(cid:863) fro(cid:373) the plas(cid:373)a. The clearance cglucose is zero at these concentrations of aglucose. At a certain point (threshold), the filtered glucose exceeds the transport capacity of the tubule to reabsorb the glucose (tm), and glucose begins to appear in the urine (is excreted). The rate at which glucose appears in the urine is equal to the rate at which it is filtered, hence curve #3 approaches that for curve #1.