NURS 505 Study Guide - Quiz Guide: Bone Pain, Growth Factor, Sucrose
Document Summary
Class/category: po4 scavengers, calcium salt, urea cycle disorder treatment agent. Indications: hyperphosphatemia in end stage renal failure (on dialysis). Mechanism: chelates phosphate and other anions in the intestine to form insoluble calciul phosphate, which is excreted in the feces. Interactions: ceftriaxone, demeclocycline, dolutegravir, doxycycline, eltrombopag, lymecycline, minocycline, oxytetracycline, tetracycline. Contraindications: ceftriaxone, allergy, renal calculi, hypercalcemia, hypophosphatemia, concurrent calcium supplements. Adverse effects: hypercalcemia, anorexia, coma, confusion, delirium, headache, n/v, arrhythmias, hypomagnesaemia, hypotension, weakness. Dose: 2 capsules (1334mg) po with each meal incleases to 3-4 capsules (2001-2868mg) Mechanism: polymeric phosphate binder; decreases serum phosphate concentrations without changing calcium, aluminum, or bicarbonate concentrations. Adverse effects: n/v, diarrhea, dyspepsia, nasopharyngitis, limb pain, pruritus, arthralgia, bronchitis, dyspnea, hypertension. Average dose would be 1600-2400mg po with meals. Mechanism: stimulates calcium and phosphate absorption from the small intestine; stimulates phosphate resorption at renal tubule; stimulates secretion of calcium into blood from bone. Gi, live, or biliary disease associated with malabsorption of vitamin d analogues.
