01:146:328 Midterm: Table of Tissue Nematodes
7 Nov 2018
School
Department
Course
Professor
Name
Trichanella spiralis
Anisakis simplex
Dracunculus medinensis
Class
Adenophorea
Secernentea
Secernentea
Morphology
Adult: Really long esophagus,
stichosome
No Eggs – females produce L1’s
Can physically see the L3 in the infected
fish
Female is ovoviviparous and
primarily found in skin in blister
Life Cycle: DH & IH
One Host for IH and DH
DH = Marine animal
1st IH = Crustacean
2nd IH = Fish with L3 transmission stage
DH = human
IH = copepod
Adult Lives in
Intestinal epithelial cell in small
intestine
* L1 transforms the Muscle fiber
into a Nurse Cell *
Human is the wrong host
Infected fish is ingested and L3 invades
the stomach / intestinal wall
L3 released in duodenum
penetrate and migrate to
inguinal regions where it molts
to an adult
Pathology
1. Intestinal
- Lesions, nausea, diarrhea
2. Migration
- Muscle pain, breathing problems
3. Inflammatory
- Heart damage, nervous damage
Acute: pain and nausea
Chronic: abscesses, granulomas, host
immune
Abscess
Secondary infection
Arthritis
Blister
Diagnosis
ELISA
Detects ESA – excretory secretory
antigen
Recent consumption of raw fish
ELISA for circulating antigen
Blister with worm
Treatment
Albendazole and Mebendazole
Albendazole and Mebendazole
Physical removal over time
