BIOL 4376 Study Guide - Midterm Guide: Pharmacophore, Nelfinavir, Drug Design
28 Jul 2020
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Both 7 and 8- a 3-dimensional arrangement of functional groups on drug (complementarity with. 10. true or false- therefore, at low concentrations many drugs will bind additional subtypes leading ae"s. The physicochemical properties that this specific arrangement (the electronic and lipophilic. 14. pharmacophore- active portion of molecule that is interacting with our selective receptor. 14. 5 true or false: the 3-d arrangement of functional groups in a drug responsible for specific drug- receptor interactions at target receptors: drugs within the same class fulfill pharmacophoric requirements for a specific receptor subtype. Hiv-1 protease: nelfinavir: true or false- agonists and antagonists for the same receptor may have the diff pharmacophores. 17. drug example that can be traced to structure-based methods: structure design- suitable for clinical testing, ligand based design . Is the design and optimization of a chemical structure with the goal of identifying a compound.
