NSCI 1051 Study Guide - Serotonergic, Glutamatergic, Tryptophan

• School: Temple University
• Department: Neuroscience - CLA
• Course: NSCI 1051
• Professor: Stefanatos

Document Summary

Voltage gated calcium channels in the presynaptic membrane open, calcium ions enter the presynaptic neuron: calcium ions cause synaptic vesicles to fuse with the presynaptic membrane, releasing neurotransmitter into the synaptic cleft, neurotransmitter diffuses cross the synaptic cleft and binds to specific neuroreceptor sites in the postsynaptic membrane, sodium channels open. Sodium ions diffuse into the postsynaptic membrane causing depolarization, which may initiate an action potential: enzymes (e. g. acetylcholinesterase breaks down neurotransmitter (e. g. acetylcholine). Plays a role in cognition (attention to external events, planning and executing movement), emotions (fear and anxiety): deficiencies result in difficulties concentrating, fatigue, not feeling empathy and depression, clinically relates to depression and. Synapses that use gaba: regulates mood, emotional behavior (anger) sleep, modulation of body temperature, human sexuality, appetite (carb craving), metabolism, stimulating vomiting, raphe nuclei are the principal source, serotonin reuptake blocked by of serotonin (5 ht) release antidepressants, either reloaded into vesicles or degraded by mao, dopamine, norepinephrine,