CHEM 3310 Midterm: Exam 2 Review
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[e]t = [e] + [es: v0 = k2 [es, k2[e]t= vmax, k1[e][s]= kt[es] + k2 [es, v0= vmax [s] Km: km= (k -1 + k2) (units of concentration, i. e. m) (michaelis. K1 constant: when [s] = km, v0= vmax, km is substrate concentration that yields velocity, when [s] is lower than km, the velocity is slow, when [s] is higher than km, the velocity is fast. O2 -> fe (ii) shift out from plane to porphyrin plane: binding of oxygen sends signal, all life in this room relies on distance of 0. 4a xi. hemoglobin follows aspects of both the sequential and concerted models xii. Bohr effect: protons (low ph) and co2 promote t-state: decreasing ph incr eases [h+, (cid:271)i(cid:374)ds o(cid:454)(cid:455)ge(cid:374) (cid:449)o(cid:396)se, so it(cid:859)s (cid:271)ette(cid:396) at gi(cid:448)i(cid:374)g it up, high [co2]- more oxygen released, co2 acidifies environment xiv. T- more sigmoidal and r- more hyperbolic xv. lower ph facilitates formation of salt bridge between beta and alpha subunits xvi.
