FRSC 367 Study Guide - Midterm Guide: Selective Serotonin Reuptake Inhibitor, Forensic Toxicology, Forensic Pathology
11 Dec 2016
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Forensic toxicology: examination of all toxicity aspects that have legal distinctions. Assist forensic pathologist by comprehensive analyses of toxins. Ed 50 : effective dose-dose that will lead to desired response in 50% of test population. Ld 50 : toxicologically lethal dose -dose that will lead to death in 50% of test population. Postmortem drug testing: determine what is specific toxin. Goal of toxicologists: collaborate with forensic pathologist in determining cause and manner of death. Testing process: blood, urine, gastric contents, vitreous humor estimating time of death, liver, bile. Major categories of medicinal agents involved in deaths. Antidepressants tricyclic antidepressants, antidepressants, selective serotonin uptake inhibitors. Nonmedicinal agents are ones normally encountered in the environment or in normal social activity. Examples are: alcohol, cyanide, carbon monoxide, hydrocarbons. Rule of thumb: 1. 5 oz of alcohol raises blood conc. Identify which test is used for: identifying the sample, separating sample into individual components, screening the sample.
