NUR 326 Study Guide - Midterm Guide: Spironolactone, Phlebitis, Tendinosis
3 Nov 2016
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Prednisone corticosteroid; anti-inflammatory: inhibits prostaglandin synthesis and suppresses histamine release & inhibits phagocytes and lymphocytes, ae: suppresses adrenal gland function so long term use . Pu, electrolyte imbalances, osteoporosis: keep dose as low as possible, use alternate-day dosing, & discontinue gradually, can mask infections causing them to grow rapidly & undetected. Ci in active infections: administer im injections deep into muscle mass, adjustment of insulin or oral hypoglycemic drugs for diabetic pts, labs: inhibited antibody response, hyperglycemia; ca, k, & thyroxine. Acetaminophen centrally acting cox inhibitor; antipyretic & analgesic, Not anti-inflammatory: reduces fever by direct action @ level of hypothalamus & dilation of peripheral blood vessels sweating off heat to get rid of fever, hepatotoxicity; ci in chronic alcoholism, no more than 3g/day!!! Of n-acetylcysteine (acetadote), it protects liver from toxic metabolites of acetaminophen. Hepatitis b vaccine: provides active immunity against hep. 2: ci: pts. w/ hypersensitivity to yeast or hbv.
