NUR 326 Study Guide - Final Guide: Serotonin Antagonist, Cardiac Arrhythmia, Beta Blocker
22 Aug 2016
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Cholinergics (muscarinic agonists): these work on the parasympathetic nervous system (rest and digest); ach is main neurotransmitter (neuropharmacology, slide 13) Anticholinergics (muscarinic antagonists): blocks the actions of ach at muscarinic receptors to prevent rest and digest. (neuropharmacology, slide 14) Cholinesterase inhibitors: binds to ache to prevent breakdown of ach [ ach availability = rest & digest. ] (neuropharmacology, slide 15) Local anesthetics: suppress pain by blocking na channels & blocking the impulse of pain; effects extended with epinephrine. A/e: cns excitation depression, bradycardia, heart block, contraction, cardiac arrest, hypotension. & cardiac depression, malignant hyperthermia (treated with dantrolene), aspiration, hepatotoxicity. (pain and anesthesia, slide 14) Od: coma, respiratory depression, pinpoint pupils. (naloxone + o2) Opioid antagonists: reversal of respiratory and cns depression; reversal of pain relief, reversal of neonatal resp. depression, addiction. Serotonin receptor agonists (triptans): used to treat migraine headaches. Ache which ach levels (which were 90% gone w/ ad) Bethanechol (urecholine, duvoid) used for urinary retention (gerd, abd. distention.
