PSY 220 Study Guide - Midterm Guide: Spina Bifida, Synaptic Pruning, Neural Tube

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Neurulation: the process when the neural plate forms a tube: starts 2 weeks after birth, early embryonic stage. The forward end of the neural tube differentiates into the hindbrain, midbrain, and forebrain. Failure of neural tube closure during embryonic development in the spine: spina bifida. Failure of neural tube closure in the brain during embryonic development: anencephaly. Differentiation: refers to the forming of the axons and dendrites that gives the neuron its distinctive shape (the maturation) in the central nervous system myelination occurs in the following order: spinal cord, hindbrain, midbrain, forebrain. The last part of the brain to develop: prefrontal cortex (the telencephalon) The required processes in a normal development of neurons in the brain: synaptogenesis, synaptic pruning, migration, myelination, differentiation, Synaptogenesis is the fourth stage in neuronal development and refers to the formation of the synapses between neurons though out life. Most central nervous system pruning occurs after 10 years of age.

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