BIS 103 Study Guide - Final Guide: Atp Citrate Lyase, Malonyl-Coa, Fatty Acid Synthase

• School: UC-Davis
• Department: Biological Sciences
• Course: BIS 103
• Professor: Fiehn Oliver

Document Summary

Insulin has a + b chain, made in beta-cells of pancreas: comes from tyrosine, hormones have different classes (ie: lipid-derived, polypeptides, etc. , do(cid:374)"t k(cid:374)o(cid:449) (cid:374)a(cid:373)es of diseases just know what happens when something does not work. Lipoprotein: single layer of membrane lipids, outer = polar heads, inner = fatty acids, cholesterol esters also needed to modify fluidity of membrane. Activate carboxylase store in liver and export to fat: malonyl-coa more = make palmitic acid, less = burn palmitic acid. Isomerase: polyunsaturated fatty acids, 1st use nadph and reductase, then use isomerase, nadph comes from pentose phosphate pathway or malic enzyme. Regulation: use insulin to take off molecules high in concentration, lots of glucose insulin causes oxidation. Insulin with acetyl-coa lots of acetyl-coa store away somewhere. Fatty acid synthase complex 7 enzymes: acyl carrier protein (acp) carries acyl groups (thioester linkage, ketoacyl-acp synthase (ks) takes acyl group and adds malonyl group.