BIS 104 Study Guide - Midterm Guide: Benign Tumor, Petri Dish, Cervical Cancer
Document Summary
Lecture 1 introduction to cell biology and cancer biology. Usa 1. 5 million cases of cancer per year. 35%-45% of you all will have cancer. Ionizing radiation cant avoid, but can avoid large amounts. Virus hpv sexually transmitted -> cervical cancer (90%) Inflammation asbestos used for construction on wall or tiles. Benign tumor constrained in place, doesn"t invade other tissues. Malignant invade and disrupts other tissues. Cancer tumor malignant, lost control of division (over dividing) and invasive. All cells of a tumor or a secondary tumor derived from a single cell. Primary tissue culture cells adhere to petri dish: cell to cell contact, need growth factor (ex: serum or broth) Transformed cells cancer like cells: grow without adhering, grow in contact with other cells, undifferentiated, avoid apoptosis, immortal, when injected into mice, it can form tumors. Multiple mutations accumulated in a single cell required for cancer. Mutation of genes that can lead to cancer.