CHEM 153A Study Guide - Final Guide: Atp Synthase, Oxidative Phosphorylation, Succinic Acid

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Small molecules can permeate the outer membrane due to transmembrane channel porins. Inner membrane is impermeable (selectively permeable) to most small molecules and ions (even h+) Where respiratory electron carriers for etc and the atp synthase are (on the surface) More profuse cristae/ larger area in heart mitochondria => > 3x many sets of etc system compared to liver mitochondria. Segregate the intermediates and enzymes of cytosolic metabolic pathways from those of metabolic processes in the matrix. Require specific transporters to carry pyruvate, fatty acids, aa, alpha-keto derivatives and adp + pi (as newly synthesized atp is transported out of the inner membrane) into the matrix for access to the machinery of cac. Ensure the beginning and end of glycolysis is running at the same rate. Into respiratory chain by universal e carriers (nicotinamide nucleotides: nad+/ nadp+ By removing 2 hydrogen atoms (one transferred as h- To nad+; one released as h+) from their substrates as.

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