MCD BIO 138 Study Guide - Midterm Guide: Signal Transduction, Oogenesis, Microtubule

• School: UCLA
• Department: Molecular, Cell, and Developmental Biology
• Course: MCD BIO 138
• Professor: karenlyons

Document Summary

Gurken in a/p is deposited in the eggs by the nurse cells. translated in egg before fertilization and secreted before binding to torpedo receptors on the adjacent follicle cells. This activates a signal transduction pathway in follicle cells. The follicle cells send a signal back to oocyte that causes reorganization of microtubules in the oocyte. Gurken in the d/v is the cause of microtubule reorganization. mrna is translated here and creates a new localized source of gurken protein. Deposited by nurse cells moves to the region around the nucleus. Signals to the adjacent follicle cells to specify them as dorsal. Signaling to dorsal follicle cells leads to differences in gene expression in dorsal vs ventral follicle cells. Maternal genes: what are the maternal genes we discussed in class that control: Prior to fertilization: cell-cell interactions (oocyte-follicle cells) establish a/p axis: to localization of maternal mrnas along a/p axis of embryo.