PNB 2265 Study Guide - Midterm Guide: Myelin, Action Potential, Chronic Pain

• School: UConn
• Department: Physiology and Neurobiology
• Course: PNB 2265
• Professor: Kristen Kimball

Document Summary

Unipolar neurons: primary sensory afferent: any info coming from skin receptors, extroreceptors in skin. Afferent neuron: primary afferent wired to receptors, originating from sensory receptors. Efferent neuron: go out to some muscle, gland, corticospinal. Exceptions cell bodies in dorsal root ganglia (unipolar sensory neurons, pns: no synapses) Quickly adapting receptors: info that changes, stop adapting to a long stimulus. Slowly adapting receptors: continue to sense long term pain. Action potential at node of ranvier, positive inside (reversal) due to na channels. Internodes: do not leak currents, charge is negative inside, local current travels to next node to threshold generating next ap. Local currents try to go both ways but only move forward because previous node is in refractory. Local currents carry signal to next node, fast.