PCB 4723C Midterm: pcb4723C exam 2 outline

• School: University of Florida
• Department: Process Biology
• Course: PCB 4723C
• Professor: Galaxia A Cortés- Hinojosa

Document Summary

Topic 1: transport related diseases- diarrhea hypertension kidney stone disease cystic fibrosis. Proportional to the concentration of nonpenetrating solute: unassisted membrane transport, assisted membrane transport, channels- highly selective, formed by transmembrane proteins, ions or water (aquaporins), faster than carrier-mediated. Leak channels- open all the time: carrier-mediated transport- transmembrane proteins that can undergo reversible changes in shape, small water soluble substances, facilitated diffusion or active transport, binding sites on either side of membrane. Facilitated diffusion- passive with the concentration gradient. Conformational change: ex: glucose transport into cells. Endocytosis and exocytosis- must be balanced in order to maintain constant membrane surface area and cell volume. Caveolae- may play a roll in transport and cell signaling: p-type atpases- na/k, h/k, ca, na/k atpase: 3 na out for every 2 k in. splits atp for energy which makes phosphorylation induce shape change. Na and k concentration gradients across plasma membrane: v type atpase- h-atpase.