CHEM 2302 Study Guide - Final Guide: Peptide Synthesis, Polystyrene, Isoelectric Point
Document Summary
1: (28 pts) l-tyrosine is one of the twenty common amino acids. As shown at right, the side-chain -oh of tyrosine has a pka = 10. 2: tyrosine can exist in different charge states, depending on solution ph. In the boxes below, draw three full chemical structures of tyrosine that you would expect to find at different ph values. Draw structures with a total charge of +1, 0, and -1. tyrosine pka = 10. 2 ion; Tyrosine has three functional groups that can participate in acid-base reactions at ph values in water (between 1 and 14): The amine, which in acid is protonated to make an ammonium the carboxylic acid; and the phenolic -oh. Under extremely acidic conditions (say, at ph = 1), all of these groups would be protonated, and we can directly compare the acidity (pka) of each functional group.
