BIOL 540 Midterm: exam 2 summary
Document Summary
Functions: protection of molecules (usually membrane protein and membrane lipids, localization: cell-to-cell communication, recognition: help cells recognize where to go. Factors that affect glycosylation: proteins, glycosyl groups activated monomers catalysts (glycosyltransferase) Starts in er and is completed in the golgi apparatus. Recognized by sequence asn-x-thr/ser as it enters the er. No consensus sequence, but sugars are bound to serine or threonine hydroxyl group. Post-translational modification: there are two general classes of n-linked glycoproteins, high-mannose: has a lot of mannose glycosyl groups, complex: has a lot of different glycosyl groups. Substrate specificity: a preference of something; can potentially use other things but prefers a specific one. Partial proteolysis: breakdown of proteins into smaller polypeptides or amino acids. Cuts off things like localization peptides the sequence that tells a protein where it needs to go: disulfide bonds must be formed so that the protein does not fall apart once it is secreted.
