BIO 242 Study Guide - Quiz Guide: Hematopoietic Stem Cell, Erythropoietin, Erythropoiesis
Document Summary
Transport oxygen and carbon dioxide between tissues and lungs: appearance: Heme = iron attaches to polypeptide chain (increased affinity for oxygen) Globin = 4 chained polypeptide: last for about 120 days, make up 45% of blood, erythropoiesis. Stimulated by low oxygen carrying capacity: kidney releases erythropoietin (hormone) into blood and bone marrow. Rbcs production increases: developed in hematopoietic stem cells in bone marrow, stimulated by erythropoietin, requires: iron, folic acid, and vitamin b12, spleen filters out old rbcs, liver breaks down rbcs and stores iron. Dark-staining nucleus: developed in hematopoietic stem cell in bone marrow (like rbcs, either become myeloid or lymphoid, 5 types of leukocytes, neutrophil, phagocytizes microorganisms and other substances. Anemia: anemia = decrease in the oxygen carrying capacity of blood, low hematocrit result from decrease in erythrocytes number or size, 6 categories of anemia. Nutritional anemia: caused by iron deficiency, less hemoglobin for the erythrocytes, decreased production of red blood cells.
