BIO 352 Study Guide - Midterm Guide: Polyploid, Chromosomal Translocation, Epistasis

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20 Jun 2018
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Old Exam 2
1. You are studying a new species of toad that exists in two forms, bumpy an smooth. You
find that when bumpy females are mated to smooth males the offspring consist of bumpy
males and smooth females, whereas when smooth females are mated with bumpy
males the offspring of both sexes are all bumpy. All strains mated are true-breeding. You
would conclude that the _____ allele is dominant and that _____ are the heterogametic
sex ( the sex with two different chromosomes) in this species
a. Bumpy, females
2. Why are triploid species rare?
a. Chromosomes in triploid cannot segregate equally during meiosis causing
sterility.
3. Chromosome nondisjunction results in which of the following human genetic disorders?
a. Klinefelter and Turner Syndrome
4. In Drosophila, the white eyes gene is on the X chromosome, and the w (white) is
recessive to w+ (red). A red-eyed male is mated to a white-eyed female and produces
many white-eyed sons, many red-eyed daughters, and one red-eyed son. What is the
most likely sex chromosome constitution of the red-eyed son?
a. XXY
5. Why do mapping experiments become less accurate when the distance between linked
genes become large?
a. Multiple crossovers are more common
6. In Humans, XXY individuals are males with Klinefelter's syndrome. WHich of the the
following events could not give rise to a Klinefelter male?
a. Nondisjunction at meiosis II in the father.
7. In tetrad analysis, second-division segregation patterns (2:4:2 or 2:2:2:2) result from:
a. Single crossovers between a gene and a centromere
8. In chicken, it is the females that have two different sex chromosomes (Z and W) while
the males have two Z chromosomes. A Z-linked gene controls the pattern of feathers
with the dominant B allele causing the barred pattern and the b allele causing non-
barred feathers. You cross a barred female with a non-barred male. What do you expect
for the phenotype of the progeny?
a. Daughters of all one type, sons of all the other type
9. A human with turner's syndrome would represent
a. More than one of the above
a.i. (an aneuploid condition)
a.ii. (A monosomic condition)
10. A transfer of genetic material between two non-homologous chromosome is called:
a. A reciprocal translocation
11. Because of translocation involving non-homologous chromosomes, a growth gene
suddenly finds itself expressed at a much higher rate and the cell becomes cancerous.
This activision of the growth genes is because of:
a. Position effects
12. In a reciprocal translocation heterozygote, what is the pattern of homologus
chromosome association during synapsis?
a. A cross shaped configuration of four chromosomes is formed
13. Triploids
a. All except one of the above
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Document Summary

Old exam 2: you are studying a new species of toad that exists in two forms, bumpy an smooth. You find that when bumpy females are mated to smooth males the offspring consist of bumpy males and smooth females, whereas when smooth females are mated with bumpy males the offspring of both sexes are all bumpy. In drosophila, the white eyes gene is on the x chromosome, and the w (white) is recessive to w+ (red). A red-eyed male is mated to a white-eyed female and produces many white-eyed sons, many red-eyed daughters, and one red-eyed son. What is the most likely sex chromosome constitution of the red-eyed son: xxy, why do mapping experiments become less accurate when the distance between linked genes become large, multiple crossovers are more common. In humans, xxy individuals are males with klinefelter"s syndrome. Which of the the following events could not give rise to a klinefelter male: nondisjunction at meiosis ii in the father.

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